Wednesday, December 5, 2012

Traffic Signals at Tunnel in Japan


Mountains account for about 70 percent of Japan’s land area, so there are a lot of tunnels across the nation. In Japan, the longest tunnels are the Seikan Tunnel (53,850 meters) between Honshu (the main land) and Hokkaido in railroads, and the Tokyo-bound lanes of the Kan-etsu Tunnel (11,055 meters) between Gunma and Niigata Prefectures on the Kan-etsu Expressway in roads for vehicles.

Concrete ceiling panels collapsed in the Sasago Tunnel on the Chuo Expressway in Yamanashi Prefecture on December 2, killing nine people. The Tokyo-bound lanes of the tunnel, where the accident happened, are 4,784 meters long and opened in 1977. An official of the expressway operator Central Nippon Expressway Co. (NEXCO-Central) said that the aging of the tunnel was one of the strongest triggers of the accident.

The panel was fixed to the top of the tunnel using metal hanger support rods and bolts. Aging degradation may have caused the collapse. There are at least 29 tunnels built in the same way as the Sasago Tunnel on expressways in the nation. The Land, Infrastructure, Transport and Tourism Ministry began nationwide examinations of such tunnels.

Only the Sasago Tunnel has never been checked for any noises by hammering the hanger support rods in five tunnels managed by NEXCO-Central that have the same structure as the Sasago Tunnel, according to Jiji Press.

By the way, you may have seen traffic signals at an entrance to a long tunnel on an expressway.

There was a severe traffic accident in the Nihonzaka Tunnel (2,050 meters at the time) on the Tomei Expressway in Shizuoka Prefecture in 1979. The crash involving several vehicles led to a fire, killing seven people. (In 1998, the tunnel was reconstructed to ease chronic traffic jam, becoming 2,555 meters long.)


I cannot forget the Nihonzaka Tunnel crash accident. When it happened, I was eight years old. I and my family drove through the tunnel just before the crash. If we had been there a few hours later, we would have been involved in the crash…

Since the accident, traffic signals have been installed at entrances to long tunnels. Of course, if it is red, you must stop immediately even when on the expressway.



The picture above is an entrance to the Enasan Tunnel (8,650 meters) on the Chuo Expressway, showing the signals are yellow: “A traffic jam in the tunnel, so you must drive carefully.”

Tuesday, December 4, 2012

Amitiza, a new type of laxative launched in Japan


A new type of laxative, lubiprostone (Amitiza®), appeared this November in the Japanese market. It is the first medicine that meets the indication of chronic constipation, characterized by less development of tolerance. Amitiza® can be safely used for a long period. It may also be administered to patients with reduced renal function who cannot use magnesium oxide, which might raise serum magnesium ion levels enough to cause fatal arrhythmia. Speaking of laxatives, many people would have an image of “inexpensive prices.” But a capsule of Amitiza® costs 156.5 yen, much more expensive than existing laxatives. Moreover, it needs to be taken twice a day.



As you can see, the structural formula shows that it is a kind of prostaglandins. Prostaglandin preparations remind us that they are usually expensive. This is true.

Lubiprostone is not metabolized in the small intestine and combines with a type 2 chloride channel (ClC-2) on the apical aspect of gastrointestinal epithelial cells, opening the channel. Chloride ions are pumped out of the cell, which produces a chloride-rich fluid secretion. The secretion softens the stool, increases motility and promotes spontaneous bowel movements. This mechanism is similar to that of a traditional laxative magnesium oxide, which increases the osmotic pressure in the intestine and softens the stool.

The Health, Labor and Welfare Ministry approved manufacturing and distribution of Amitiza® indicated for chronic constipation (excluding constipation caused by structural disease) this July. It is the first laxative that received approval to treat “chronic” constipation, developed by SUCAMPO Pharmaceuticals in Maryland, the U.S. and domestically distributed by ABBOTT JAPAN Co., Ltd. It was released November 22 following the National Health Insurance price listing.

Distribution of the medicine was approved for patients with chronic idiopathic constipation in the U.S. in 2006 and in Switzerland in 2009. Besides, it received approval to treat chronic irritable bowel syndrome in the U.S. in 2008. The medicine is now under application for an indication extended to opioid-induced constipation.

Sunday, November 25, 2012

Omega 3 fatty acids don't reduce cerebrovascular risk


Reduced cerebrovascular risk by fish intake not derived from omega 3 fatty acids: 
meta-analysis of 26 prospective cohort studies and 12 randomized controlled studies

Fish is good for the health. This is widely believed over the world. It is thought that Japanese people live the longest because they eat a lot of fish. Long chain omega fatty acids rich in fish are thought to be effective against cerebrovascular risk, which has been denied by a report on the BMJ. The fact will shake medical providers including doctors and pharmacists, and some pharmaceutical companies producing eicosapentaenoic acid (EPA) as a medication for arterial sclerosis. Many supplements containing EPA and docosahexaenoic acid (DHA) are available at a drugstore. They are very popular among those who want to keep young and healthy.

What are omega 3 fatty acids?

 

The chemical structural formula above of eicosapentaenoic acid (EPA)(20:Δ5c,8c,11c,14c,17c), one of essential omega 3 fatty acids, meaning that it has five double bonds at the 5th, 8th, 11th, 14th and 17th carbons of the whole carbon chain. Chemists number carbons from the carbonyl carbon (blue), but physiologists do from the ω carbon (red). The first double bond appears at the 3rd carbon from the ω carbon in EPA, which is called ω-3.

Fish is one of the foods which have an effect on cardiovascular protection. Benefits brought by eating fish are thought to be derived from ω-3 unsaturated fatty acids. Rajiv Chowdhury and his colleagues of University of Cambridge in the United Kingdom, however, performed a systematic review and a meta-analysis of observational studies and randomized controlled studies, revealing that cerebrovascular event risk significantly dropped with increased fish intake, but ω-3 fatty acids themselves did not significantly provide any benefits. The paper was published on the British Medical Journal online on October 30, 2012.



The full text is available at:




Friday, November 23, 2012

豊川信用金庫立てこもり事件

豊川信用金庫蔵子(ぞうし)支店、立てこもり事件。びっくりです。

Arachanが生まれ育った豊川ですから。当時住んでいた家から徒歩で15分くらいでしょうか。


夕方からTVで盛んに報道されていました。すぐに解決されると思いきや、日付をまたいだ未明に犯人確保。長かった。人質の皆さん、この終末ゆっくり休んでください。しっかり残業手当をもらってください。これも仕事の一環です。

この豊川信用金庫、1973年に起きた「豊川信用金庫事件」で有名。

当時僕は3歳だったので記憶にございませんが、大学の一般教養「心理学」の授業で取り上げられました。

下校途中の女子高生が電車内で発した何気ない一言を発端に、取り付け騒ぎにまで発展したという事件。

もちろんデマです。

なぜ、特別に有名なのかというと、デマがどのように伝わって数千人に及ぶほどの騒動になったのか詳細に解明されたため。

以下のリンクWikipediaに記載のある、「交差ネットワークによる二度聞き効果」(別々の人から同じ情報を聞くことで、それに信憑性があるものと思い込んでしまう現象)は、なるほどな~、身に覚えがある・・・と感じました。

みなさん、デマには気をつけましょう!

この取り付け騒ぎから時がたち、状況は異なりますが、今は今で、ネットで様々な情報が手に入ります。ある意味新たなデマ騒ぎが起きても不思議ではありません。

怪しい情報があれば裏をとりましょう。


Wednesday, November 21, 2012

Jack and Jill


I've heard that an effective way to learn another language is to find some movies you really like and watch them repeatedly without Japanese subtitles.

One of my favorite films is “Jack and Jill,” which was criticized as “worst.” It was the 32nd Annual RAZZIE Awards “Winner” for Worst Picture 2011. I have no idea why it was treated as the worst movie. Some people said that it was a plagiarism or remake of “Glen or Glenda,” which was also ranked as one of The 50 Worst Movies Ever Made. That might have been one of the reasons Jack and Jill received negative reviews.

Despite such stern criticism, I really like it. It is a simple comedy film that makes me laugh a lot every time I watch it.

Story:
A successful executive of an ad agency, Jack (Adam Sandler), who has a beautiful wife and children in Los Angeles, has to experience an annual event, Thanksgiving, when his twin sister, Jill (also Adam Sandler), comes to his home. Her visit forces him to have a hard time...


Saturday, November 10, 2012

Finished Watching the "Saw" Series


I finished watching the entire series of a scary movie Saw: Saw 1-6 and the Final.
A friend of mine has lent me the DVDs, which froze me in horror.

It was way too scary to understand its full details.
Actually, I wasn't able to partly watch terrifying scenes.

In each series, people who don’t value their lives are confined by a leading character Jigsaw, who imposes atrocious games for survival on them as punishment.

Although he has fatal brain tumor, he inflicts cruel punishments on them.

To survive, 
  they will be cutting part of their body themselves...
  they will have to resolve difficult questions Jigsaw gives...
  and more...
If they fail to win the games, they will be killed one by one in cruel ways.

In the middle of the series, Jigsaw dies of the disease. But later he is still alive. I wasn't able to understand why he was alive again, filling me with question marks...

I think scenes go and come between the past and the present.

Furthermore, a detective is involved in Jigsaw’s actions.

The stories are too complicated for me. I need to watch them again and again to grasp the details.

Despite its complexity, I strongly recommend the Saw series, if you are interested in horror movies.

Click below to see an IMDb search result for Saw:

Friday, November 9, 2012

翻訳勉強に有効な心がけ

このブログの住人(Members of Daily Yomiuri Translation Club)は、英語の勉強に興味があり、特に『翻訳』という観点からの繋がりが強い。そのメンバーのひとりである(YASU)が思うところの、翻訳勉強に有効と思われる心がけを記しておきたい。
  • 一緒に勉強する友達を作ること
なぁんだ当たり前すぎて拍子抜けした、と思う人もいるかもしれないが、とっても真面目に最重要事項の一つである。翻訳は孤独な作業だが、仲間と切磋琢磨して技術向上を図ることができればこれほど素晴らしいことはない。英語勉強に必須である『継続性』の観点からも重要だ。
  • 毎日、英語および日本語と格闘すること
これまた普通すぎるかもしれないが、日々少しずつでも成長していくことがどれだけ大事かを再認識しておきたい。翻訳技術は、スポーツの技のようなものだ。得意技をどれだけ作れるか(ホームラン?)、苦手なものでも上手く処理できるか(内野安打?)、翻訳神経を毎日、休みなく鍛えていかなければならない。
突き詰めると語学の勉強というのは果てがない。なので、どうしても途中でしんどくなる。歩くのをやめると、前居たはずの場所にさえ居ることができず、どんどん後退していってしまう。でも、進んでいると段々と楽になって、いつの間にか疲れにくくなったり、ペースが少し速くなったりしているものだ。

どこか人生の教訓にも通じるところがあるかもしれない。